The Kappa Opioid Receptor: From Addiction to Depression, and Back | Semantic Scholar
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling
Early life stress dysregulates kappa opioid receptor signaling within the lateral habenula - ScienceDirect
Opioid receptors: distinct roles in mood disorders | Semantic Scholar
In major depression, increased kappa and mu opioid receptor levels are associated with immune activation | Acta Neuropsychiatrica | Cambridge Core
Frontiers | A Trigger for Opioid Misuse: Chronic Pain and Stress Dysregulate the Mesolimbic Pathway and Kappa Opioid System
Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice - ScienceDirect
Brain Sciences | Free Full-Text | Shared Mechanisms of GABAergic and Opioidergic Transmission Regulate Corticolimbic Reward Systems and Cognitive Aspects of Motivational Behaviors
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect
Opioid receptor modulation of neural circuits in depression: What can be learned from preclinical data? - ScienceDirect
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
Role of kappa-opioid receptors in stress and anxiety-related behavior. - Abstract - Europe PMC
Opioid receptors: distinct roles in mood disorders | Semantic Scholar
Scientists Take a Big Step toward Building a Better Opioid | Newsroom
Opioids in cancer: The κ‑opioid receptor (Review)
Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications
Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect
IJMS | Free Full-Text | Stress-Induced Changes in the Endogenous Opioid System Cause Dysfunction of Pain and Emotion Regulation
J Clin Med Res
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect
Dynorphin, stress, and depression | Semantic Scholar
Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects
The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence
Development of κ Opioid Receptor Antagonists | Journal of Medicinal Chemistry
Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink
